Learn how GA4GH helps expand responsible genomic data use to benefit human health.
Learn how GA4GH helps expand responsible genomic data use to benefit human health.
Our Strategic Road Map defines strategies, standards, and policy frameworks to support responsible global use of genomic and related health data.
Discover how a meeting of 50 leaders in genomics and medicine led to an alliance uniting more than 5,000 individuals and organisations to benefit human health.
GA4GH Inc. is a not-for-profit organisation that supports the global GA4GH community.
To guide our collaborative, globe-spanning alliance, GA4GH relies on a Standards Steering Committee and an Executive Committee.
The Funders Forum brings together organisations that offer both financial support and strategic guidance.
The EDI Advisory Group responds to issues raised in the GA4GH community, finding equitable, inclusive ways to build products that benefit diverse groups.
Distributed across four Host Institutions, our staff team supports the mission and operations of GA4GH.
Curious who we are? Meet the people and organisations across six continents who make up GA4GH.
More than 500 organisations connected to genomics — in healthcare, research, patient advocacy, industry, and beyond — have signed onto the mission and vision of GA4GH as Organisational Members.
These core Organisational Members are genomic data initiatives that have committed resources to guide GA4GH work and pilot our products.
This subset of Organisational Members whose networks or infrastructure align with GA4GH priorities has made a long-term commitment to engaging with our community.
Local and national organisations assign experts to spend at least 30% of their time building GA4GH products.
Anyone working in genomics and related fields is invited to participate in our inclusive community by creating and using new products.
Wondering what GA4GH does? Learn how we find and overcome challenges to expanding responsible genomic data use for the benefit of human health.
Study Groups define needs. Participants survey the landscape of the genomics and health community and determine whether GA4GH can help.
Work Streams create products. Community members join together to develop technical standards, policy frameworks, and policy tools that overcome hurdles to international genomic data use.
GIF solves problems. Organisations in the forum pilot GA4GH products in real-world situations. Along the way, they troubleshoot products, suggest updates, and flag additional needs.
NIF finds challenges and opportunities in genomics at a global scale. National programmes meet to share best practices, avoid incompatabilities, and help translate genomics into benefits for human health.
Communities of Interest find challenges and opportunities in areas such as rare disease, cancer, and infectious disease. Participants pinpoint real-world problems that would benefit from broad data use.
See all our products — always free and open-source. Do you work on cloud genomics, data discovery, user access, data security or regulatory policy and ethics? Need to represent genomic, phenotypic, or clinical data? We’ve got a solution for you.
All GA4GH standards, frameworks, and tools follow the Product Development and Approval Process before being officially adopted.
Learn how other organisations have implemented GA4GH products to solve real-world problems.
Help us transform the future of genomic data use! See how GA4GH can benefit you — whether you’re using our products, writing our standards, subscribing to a newsletter, or more.
Help create new global standards and frameworks for responsible genomic data use.
Align your organisation with the GA4GH mission and vision.
Solve your real-world data problems with support from this valuable network of global institutions.
Work with like-minded groups committed to better data use in areas like rare disease, cancer, and infectious disease.
Share your thoughts on all GA4GH products currently open for public comment.
Solve real problems by aligning your organisation with the world’s genomics standards. We offer software dvelopers both customisable and out-of-the-box solutions to help you get started.
Learn more about upcoming GA4GH events. See reports and recordings from our past events.
Speak directly to the global genomics and health community while supporting GA4GH strategy.
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Read news, stories, and insights from the forefront of genomic and clinical data use.
Attend an upcoming GA4GH event, or view meeting reports from past events.
See new projects, updates, and calls for support from the Work Streams.
Read academic papers coauthored by GA4GH contributors.
Listen to our podcast OmicsXchange, featuring discussions from leaders in the world of genomics, health, and data sharing.
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View the latest GA4GH updates, Genomics and Health News, Implementation Notes, GDPR Briefs, and more.
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9 Jul 2018
The Global Alliance for Genomics and Health (GA4GH) has always prioritized responsible, ethical data sharing. Responsibility and the right to benefit from genomic research are at the heart of everything we do. After recent discussions in the international mainstream media, this message bears repeating.
This article is part of our quarterly series of guest blog posts from GA4GH Chair Ewan Birney, in which he expounds on the most important happenings from the previous three months and plans for the future. If you’d like to get involved with any of the work mentioned below, please contact one of our Work Stream managers.
The Global Alliance for Genomics and Health (GA4GH) has always prioritized responsible, ethical data sharing. Responsibility and the right to benefit from genomic research are at the heart of everything we do. After recent discussions in the international, mainstream media, this message bears repeating.
GA4GH is built upon the Framework for Responsible Sharing of Genomic and Health-related Data (“Framework“). Completed in 2014, this document set a new standard for how we view data sharing and scientific research. Citizens have the right for their data to be secure and protected; but in addition, the Framework is founded on the 1948 Universal Declaration of Human Rights, which states that everyone in the world has the right to benefit from science and its applications. As responsible data sharing minimizes risk and maximizes the possibility of health benefits, it is an important element of realizing that right.
Last month, about 150 GA4GH Active Contributors convened in Toronto, Canada for a face-to-face working meeting, during which we advanced the deliverables outlined in the 2018 Strategic Roadmap. One of the most important outcomes of the meeting was the development of a statement on responsible data sharing, which was truly a community effort. Initiated by Anna Middleton (Wellcome Genome Campus) and Bartha Knoppers (McGill University), the statement is intended to re-emphasise our commitment to responsible sharing and notes that “GA4GH encourages and supports the minimization of data-sharing risks and the prevention of data breaches.”
At the 6th Plenary Meeting in Basel, Switzerland in October, each of the GA4GH Work Streams will be releasing new deliverables from the Roadmap. Each of these takes the Framework and the GA4GH commitment to responsibility as its foundation.
For example, the upcoming Beacon API V1.0.0 release (expected later this month) integrates the ELIXIR Authorization and Authentication Infrastructure. This will enable any dataset to implement the Beacon Protocol and make it discoverable by the appropriate user base, and allow implementers to choose the authentication mode of potential users. This will open up a swath of learning potential, allowing the research community to query currently siloed databases without putting participant data at any additional risk and providing certainty of the data location and ownership.
Similarly, the htsget protocol, which announced five new implementations earlier this month, makes it possible for users around the globe to access genomic sequencing data without using files. This democratizing step brings us closer to genomics’ inevitable, cloud-based future and opens up new possibilities for the responsible use of genomic data to improve human health and allow citizens to benefit from scientific advancement.
In this increasingly open era of digital communications, data breaches are a foregone fact. Our focus — and our commitment to the international community — is to minimize risk and maximize benefit for every individual in the world. I look forward to watching the Work Streams tackle these impressive challenges with grace.
To learn about real-world examples of our progress in this effort, please join me at our Plenary Meeting in October. I hope to see many of you there!
Notable GA4GH Publications from Q2, 2018: