Learn how GA4GH helps expand responsible genomic data use to benefit human health.
Learn how GA4GH helps expand responsible genomic data use to benefit human health.
Our Strategic Road Map defines strategies, standards, and policy frameworks to support responsible global use of genomic and related health data.
Discover how a meeting of 50 leaders in genomics and medicine led to an alliance uniting more than 5,000 individuals and organisations to benefit human health.
GA4GH Inc. is a not-for-profit organisation that supports the global GA4GH community.
To guide our collaborative, globe-spanning alliance, GA4GH relies on a Standards Steering Committee and an Executive Committee.
The Funders Forum brings together organisations that offer both financial support and strategic guidance.
The EDI Advisory Group responds to issues raised in the GA4GH community, finding equitable, inclusive ways to build products that benefit diverse groups.
Distributed across four Host Institutions, our staff team supports the mission and operations of GA4GH.
Curious who we are? Meet the people and organisations across six continents who make up GA4GH.
More than 500 organisations connected to genomics — in healthcare, research, patient advocacy, industry, and beyond — have signed onto the mission and vision of GA4GH as Organisational Members.
These core Organisational Members are genomic data initiatives that have committed resources to guide GA4GH work and pilot our products.
This subset of Organisational Members whose networks or infrastructure align with GA4GH priorities has made a long-term commitment to engaging with our community.
Local and national organisations assign experts to spend at least 30% of their time building GA4GH products.
Anyone working in genomics and related fields is invited to participate in our inclusive community by creating and using new products.
Wondering what GA4GH does? Learn how we find and overcome challenges to expanding responsible genomic data use for the benefit of human health.
Study Groups define needs. Participants survey the landscape of the genomics and health community and determine whether GA4GH can help.
Work Streams create products. Community members join together to develop technical standards, policy frameworks, and policy tools that overcome hurdles to international genomic data use.
GIF solves problems. Organisations in the forum pilot GA4GH products in real-world situations. Along the way, they troubleshoot products, suggest updates, and flag additional needs.
NIF finds challenges and opportunities in genomics at a global scale. National programmes meet to share best practices, avoid incompatabilities, and help translate genomics into benefits for human health.
Communities of Interest find challenges and opportunities in areas such as rare disease, cancer, and infectious disease. Participants pinpoint real-world problems that would benefit from broad data use.
See all our products — always free and open-source. Do you work on cloud genomics, data discovery, user access, data security or regulatory policy and ethics? Need to represent genomic, phenotypic, or clinical data? We’ve got a solution for you.
All GA4GH standards, frameworks, and tools follow the Product Development and Approval Process before being officially adopted.
Learn how other organisations have implemented GA4GH products to solve real-world problems.
Help us transform the future of genomic data use! See how GA4GH can benefit you — whether you’re using our products, writing our standards, subscribing to a newsletter, or more.
Help create new global standards and frameworks for responsible genomic data use.
Align your organisation with the GA4GH mission and vision.
Solve your real-world data problems with support from this valuable network of global institutions.
Work with like-minded groups committed to better data use in areas like rare disease, cancer, and infectious disease.
Share your thoughts on all GA4GH products currently open for public comment.
Solve real problems by aligning your organisation with the world’s genomics standards. We offer software dvelopers both customisable and out-of-the-box solutions to help you get started.
Learn more about upcoming GA4GH events. See reports and recordings from our past events.
Speak directly to the global genomics and health community while supporting GA4GH strategy.
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Questions? We would love to hear from you.
Read news, stories, and insights from the forefront of genomic and clinical data use.
Attend an upcoming GA4GH event, or view meeting reports from past events.
See new projects, updates, and calls for support from the Work Streams.
Read academic papers coauthored by GA4GH contributors.
Listen to our podcast OmicsXchange, featuring discussions from leaders in the world of genomics, health, and data sharing.
Check out our videos, then subscribe to our YouTube channel for more content.
View the latest GA4GH updates, Genomics and Health News, Implementation Notes, GDPR Briefs, and more.
Discover all things GA4GH: explore our news, events, videos, podcasts, announcements, publications, and newsletters.
3 Dec 2021
This GA4GH Community Post is the seventh in our monthly series featuring individuals from across GA4GH. This month we are turning the spotlight on Lindsay Smith!
This GA4GH Community Post is the seventh in our monthly series featuring individuals from across GA4GH. This month we are turning the spotlight on Lindsay Smith! As the Work Stream and Clinical Projects Manager at the Global Alliance for Genomics and Health (GA4GH), Lindsay manages international teams developing standards for the responsible sharing of genomic and health-related data. Her work supports the clinical adoption of genomics through establishing standardized information models to describe clinical data for use in genomic medicine and research, including the capture and exchange of information across electronic health records, research systems, registries, journals, and patient platforms. She also supports the development of policies and frameworks that focus on the ethical, legal and social implications of international data sharing. Lindsay is a strong advocate of a global ‘learning health system’, coordinating the sharing of tools, experience, and knowledge among large-scale national genomic initiatives.
Lindsay holds an MSc in Molecular Genetics with a collaborative specialization in Developmental Biology from the University of Toronto. Prior to joining GA4GH in 2019, she was a Clinical Research staff member at the Hospital for Sick Children in Toronto, investigating potential drug targets for rare neuromuscular disorders.
What current projects are you working on?
I am the Work Stream Manager for the Regulatory and Ethics and Clinical and Phenotypic Data Capture Work Streams, Coordinator of the Genomics and Health Implementation Forum (GHIF) and a key point of contact for coordinating GA4GH’s efforts with other standards development organizations. Some of the projects I’m supporting include finalizing an extensible model for pedigree and family health history information and developing a work plan for computable cohort representation. I’m particularly excited about the topics the Regulatory and Ethics Work Stream is exploring for their new roadmap, such as newborn sequencing, blockchain and ethical provenance, and machine learning bias. Given that many of the topics lie outside of my knowledge base, I’m looking forward to having the opportunity to learn about new technologies and innovations in genomics.
How do you think genomic data standards will shape the world in 20 years?
To me, the future of standardization is enabling a world where clinical geneticists can query all of the world’s genomic datasets at once to find unanticipated gene-disease associations and solve previously unsolvable cases; in which biologists and common disease researchers can interrogate cohorts large enough to achieve the power needed to detect all significant contributors to disease; and in which all qualified researchers can participate in genomics regardless of their means or location. This vision depends on a federated system for searching, discovering, exchanging, and analyzing genomic and clinical data that is built on standards and frameworks embraced by the broad genomics and health community.
What advice would you give to individuals seeking to get more involved with GA4GH?
Just get involved, and don’t be afraid to dive right into topics that are of interest to you. I think a lot of people come in with some hesitation, thinking “I’m not enough of an expert” or “I’m joining the effort late, what could I possibly contribute now?”. The truth is that you have a unique experience and perspective from everyone else in that group, and the entire GA4GH community is so welcoming and would be happy to help bring you onboard. So join a Work Stream or two, try reviewing a standard that’s open to public review and submit some comments, even if they’re just editorial (still very important!). The worst case scenario is that you’ll learn something new about your field!