Learn how GA4GH helps expand responsible genomic data use to benefit human health.
Learn how GA4GH helps expand responsible genomic data use to benefit human health.
Our Strategic Road Map defines strategies, standards, and policy frameworks to support responsible global use of genomic and related health data.
Discover how a meeting of 50 leaders in genomics and medicine led to an alliance uniting more than 5,000 individuals and organisations to benefit human health.
GA4GH Inc. is a not-for-profit organisation that supports the global GA4GH community.
To guide our collaborative, globe-spanning alliance, GA4GH relies on a Standards Steering Committee and an Executive Committee.
The Funders Forum brings together organisations that offer both financial support and strategic guidance.
The EDI Advisory Group responds to issues raised in the GA4GH community, finding equitable, inclusive ways to build products that benefit diverse groups.
Distributed across four Host Institutions, our staff team supports the mission and operations of GA4GH.
Curious who we are? Meet the people and organisations across six continents who make up GA4GH.
More than 500 organisations connected to genomics — in healthcare, research, patient advocacy, industry, and beyond — have signed onto the mission and vision of GA4GH as Organisational Members.
These core Organisational Members are genomic data initiatives that have committed resources to guide GA4GH work and pilot our products.
This subset of Organisational Members whose networks or infrastructure align with GA4GH priorities has made a long-term commitment to engaging with our community.
Local and national organisations assign experts to spend at least 30% of their time building GA4GH products.
Anyone working in genomics and related fields is invited to participate in our inclusive community by creating and using new products.
Wondering what GA4GH does? Learn how we find and overcome challenges to expanding responsible genomic data use for the benefit of human health.
Study Groups define needs. Participants survey the landscape of the genomics and health community and determine whether GA4GH can help.
Work Streams create products. Community members join together to develop technical standards, policy frameworks, and policy tools that overcome hurdles to international genomic data use.
GIF solves problems. Organisations in the forum pilot GA4GH products in real-world situations. Along the way, they troubleshoot products, suggest updates, and flag additional needs.
NIF finds challenges and opportunities in genomics at a global scale. National programmes meet to share best practices, avoid incompatabilities, and help translate genomics into benefits for human health.
Communities of Interest find challenges and opportunities in areas such as rare disease, cancer, and infectious disease. Participants pinpoint real-world problems that would benefit from broad data use.
See all our products — always free and open-source. Do you work on cloud genomics, data discovery, user access, data security or regulatory policy and ethics? Need to represent genomic, phenotypic, or clinical data? We’ve got a solution for you.
All GA4GH standards, frameworks, and tools follow the Product Development and Approval Process before being officially adopted.
Learn how other organisations have implemented GA4GH products to solve real-world problems.
Help us transform the future of genomic data use! See how GA4GH can benefit you — whether you’re using our products, writing our standards, subscribing to a newsletter, or more.
Help create new global standards and frameworks for responsible genomic data use.
Align your organisation with the GA4GH mission and vision.
Solve your real-world data problems with support from this valuable network of global institutions.
Work with like-minded groups committed to better data use in areas like rare disease, cancer, and infectious disease.
Share your thoughts on all GA4GH products currently open for public comment.
Solve real problems by aligning your organisation with the world’s genomics standards. We offer software dvelopers both customisable and out-of-the-box solutions to help you get started.
Learn more about upcoming GA4GH events. See reports and recordings from our past events.
Speak directly to the global genomics and health community while supporting GA4GH strategy.
Be the first to hear about the latest GA4GH products, upcoming meetings, new initiatives, and more.
Questions? We would love to hear from you.
Read news, stories, and insights from the forefront of genomic and clinical data use.
Attend an upcoming GA4GH event, or view meeting reports from past events.
See new projects, updates, and calls for support from the Work Streams.
Read academic papers coauthored by GA4GH contributors.
Listen to our podcast OmicsXchange, featuring discussions from leaders in the world of genomics, health, and data sharing.
Check out our videos, then subscribe to our YouTube channel for more content.
View the latest GA4GH updates, Genomics and Health News, Implementation Notes, GDPR Briefs, and more.
Discover all things GA4GH: explore our news, events, videos, podcasts, announcements, publications, and newsletters.
19 Sep 2023
From 19 to 22 September 2023, GA4GH held its 11th Plenary meeting in conjunction with Connect working sessions. View the 11th Plenary Meeting Report and September Connect 2023 Meeting Report. Visit the event website here.
GA4GH 11th Plenary brought together organisations and individuals from the genomics and health community for keynotes, talks, and workshops focused on genomic and clinical data sharing issues that pervade diverse industries, disciplines, and communities.
Attendees had the opportunity to learn about GA4GH’s technical standards and policy frameworks and tools, which aim to break down the many barriers to data and knowledge sharing in order to advance genomic research.
The GA4GH 12th Plenary will take place in Melbourne, Australia, from (tentatively) 16 to 20 September 2024.
GA4GH Chair Ewan Birney and 11th Plenary Programme Chair David Glazer welcomed participants in San Francisco, USA, and online. Birney announced that he would become Chair Emeritus in January, and that the GA4GH Inc. Board of Directors had elected Heidi Rehm to succeed as Chair.
CEO Peter Goodhand celebrated a milestone — 10 years of collaborative efforts and groundbreaking advancements within the Global Alliance for Genomics and Health (GA4GH). Over the past decade, GA4GH has emerged as a leading force in driving responsible and effective genomic data sharing to benefit human health. This session took attendees on a journey through the evolution of GA4GH, showcasing its pivotal role in shaping the genomics landscape and vision for the future.
Speakers presented compelling success stories that demonstrate how GA4GH work has translated into transformative solutions for genomics and health. The talks covered tangible outcomes and real-world applications of GA4GH products in Europe, Japan, the United States, and internationally. These implementations facilitated cross-disciplinary collaboration, accelerated discovery, and ultimately improved patient outcomes.
This session showcased several GA4GH technical standards and policy tools and frameworks that have seen significant progress since our last Plenary meeting: Beacon, VRS, refget, and an effort focused on paediatric pharmacogenomics. Presentations and an expert panel explained how these products facilitate data sharing, interoperability, and ethical considerations across diverse sectors.
Karen Miga discussed the need to modernise the human reference genome and introduced the Human Pangenome Project, a newly-announced GA4GH Driver Project. This federated alliance of global genomics partners focuses on the development, release, global acceptance, and use of a new human pangenome resource and pangenomic tool ecosystem. The project aims to broaden studies of genetic variants that impact the effectiveness of medical treatments, influence the risk of developing diseases, and have the potential to determine personalised medical treatments.
This session explored the latest breakthroughs and cutting-edge tools that are reshaping the landscape of genomics. Topics included long-read sequences, machine learning, and artificial intelligence more generally.
The panel shared success stories, case studies, and innovative approaches that highlighted the impact of cross-sector partnerships. Speakers explored the evolving landscape of industry engagement in genomics, and the mutual benefits and challenges faced by academia and industry.
Happi discussed preempting pandemics and containing disease outbreak in West Africa. He introduced the African Centre of Excellence for Genomics of Infectious Diseases, based in Nigeria, and presented some of the successes of affiliated researchers. For example, metagenomic surveillance helped uncover outbreaks of yellow fever and other diseases. The centre also builds capacity in genomics, both in careers and facilities.
This session explored the significance of diversity in genomic datasets and the pivotal role of comprehensive cohort representation in shaping research outcomes and healthcare equity. The panel of experts shared insights, best practices, and strategies that promote inclusivity in research.
Patient advocate Patrick Sullivan discussed how doctors must go out of their way to find personalised solutions for patients with rare disease and/or cancer. He challenged attendees to make personalised care a feature, not a bug, in the system. Sullivan gave examples from his advocacy work and his own family patient story, and advice for researchers who are communicating or engaging with patients and their advocates.
Through presentations and interactive discussion, this session explored the challenges and opportunities faced when integrating genomics into medical workflows. Presenters explained how advancements are driving precision medicine to new heights.
In the second part of “Bridging the Gap,” new panellists turned to hurdles encountered when bridging the gap between scientific discovery and clinical implementation. The speakers delved into the multifaceted challenges of translating research insights into practical applications within clinical settings. They explained the strategies, innovations, and ethical considerations that guide this process.
Gregurick discussed catalysing data science in research through collaborations. She gave many examples of NIH collaborations, including efforts to connect European researchers with access to the All of Us Research Program (a GA4GH Driver Project), and work by the NIH Cloud Platform Interoperability effort (a newly-announced GA4GH Driver Project) to incorporate standards from GA4GH, HL7/FHIR, and elsewhere.
This dialogue between two eminent thought leaders in genomics covered the current landscape, challenges, and potential future directions of genomics research, data sharing, and clinical application. Ewan Birney and Heidi Rehm shared their insights into the origins of GA4GH, the impactful initiatives that have shaped its present, and their collective vision for its future impact.
CEO Peter Goodhand thanked speakers, funders, attendees, outgoing Chair Ewan Birney, and GA4GH contributors. He announced the next GA4GH Connect meeting (in Ascona, Switzerland, from 21 to 24 April 2024) and GA4GH 12th Plenary meeting (in Melbourne, Australia, tentatively from 16 to 20 September).